Topical agents for preventing and treating actinic keratosis
نویسندگان
چکیده
منابع مشابه
Long-term Efficacy of Topical Fluorouracil Cream, 5%, for Treating Actinic Keratosis: A Randomized Clinical Trial.
IMPORTANCE Topical fluorouracil was demonstrated to be effective in reducing the number of actinic keratoses (AKs) for up to 6 months, but no randomized trials studied its long-term efficacy. OBJECTIVE To evaluate the long-term efficacy of a single course of fluorouracil cream, 5%, for AK treatment. DESIGN, SETTING, AND PARTICIPANTS The Veterans Affairs Keratinocyte Carcinoma Chemopreventio...
متن کاملNew Topical Treatment Options for Actinic Keratosis: A Systematic Review.
This systematic review compared the relative efficacy of 5-fluorouracil 0.5% in salicylic acid 10% (5-FU/SA), ingenol mebutate (IMB) and imiquimod 2.5%/3.75% (IMI) for actinic keratosis on the face, forehead or scalp. Only 11 publications, relating to 7 randomised controlled trials, met inclusion criteria and it was only possible to compare the effect of all 3 treatments on complete clinical cl...
متن کاملNon-adherence to topical treatments for actinic keratosis
BACKGROUND There is limited information on the patterns of use, adherence rates, and factors that impact adherence with topical treatments for actinic keratosis (AK). OBJECTIVES To establish patterns of use and adherence with topical treatments for AK and to identify treatment-related factors that impact on adherence. METHODS A community-based, cross-sectional study was performed using a st...
متن کاملInnovative agents for actinic keratosis and nanocarriers enhancing skin penetration.
Actinic keratosis and cutaneous squamous cell carcinoma are of increasing importance with aging and increased ultraviolet light exposure in Western societies. Efficient and well-tolerated therapy is still a matter of concern. As with tumours of other organs, new target sites and innovative drugs selectively addressing them are widely looked for. Due to the relevance for DNA synthesis and thus c...
متن کاملComparison of topical 5-fluorouracil formulations in actinic keratosis treatment.
BACKGROUND Actinic keratoses (AKs) are common and may progress to squamous cell carcinoma (SCC). While cryotherapy is the most commonly used treatment for AKs, it is only suitable for treating a few lesions at a time. Topical medications such as 5-fluorouracil (5-FU) allow for more generalized treatment of AKs in the setting of multiple lesions. OBJECTIVE To evaluate and discuss clinical tria...
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ژورنال
عنوان ژورنال: Prescriber
سال: 2016
ISSN: 0959-6682
DOI: 10.1002/psb.1451